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in vivo-jetRNA®

Catalog No.
101000013
in vivo transfection reagents are the most powerful alternative to viral vectors for nucleic acid delivery. They are easy to use, cost-effective and considered as safe and efficient vehicles for RNA delivery. mRNA transfection is rapidly emerging as a promising method for nucleic acid-based therapy and offers an attractive substitute to plasmid DNA. Non-viral mRNA delivery methods have already proven their efficiency in vaccination through antigen presenting cells modification and in anti-cancer therapy by directly targeting malignant cells. The intrinsic advantage of mRNA-based immunotherapy relies on the self-adjuvant activity of mRNA and the fact that small amounts of encoded antigen are sufficient to obtain robust immune response. in vivo-jetRNA® is a transfection reagent specifically developed to deliver mRNA in vivo. This reagent can be used to target multiple organs, by using systemic or local injection routes, in various animal models. mRNA delivery using in vivo-jetRNA® is user-friendly, with a simple 2-step protocol and can be used for vaccination purposes, anti-cancer studies, genome editing using CRISPR/Cas9 method or protein replacement.
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Pack Size
  • in vivo-jetRNA® 0.3 mL with mRNA Buffer 2 x 10 mL
  • in vivo-jetRNA® 1 mL with mRNA Buffer 60 mL
Quantity

* Free Delivery for Orders SGD$250 (excl. GST) & Above.

Brand:
Specifications
101000013
Brand
Polyplus-transfection
Application
Vaccination / immunization
Cancer therapy
in vivo functional studies (Gene expression, CRISPR genome editing)
Previous Catalog No
204-10
Molecule Delivered
mRNA
No. of Transfections
1 mL is sufficient to perform at least 50 intravenous injections or 100 intramuscular injections in mouse
Targeted Organs
All organs (depending on the injection route)
Injection Routes
Various administration routes (systemic or local)
Storage
Store in vivo-jetRNA® at 5 °C ± 3°C. Do not freeze.
Provided with
mRNA buffer
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