GTX57563
- Brand
- GeneTex
- Application
- ICC/IF
WB
- Storage Conditions
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- Note
- For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
- Synonyms
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon , HEL2 , KCIP1 , MDCR , MDS , YWHAE , tyrosine 3monooxygenase/tryptophan 5monooxygenase activation protein epsilon , 14-3-3 epsilon , 1433E
- Background
- This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
- Specificity
- Based on internal testing result, this antibody does not cross react with human 14-3-3 zeta, human 14-3-3 beta, human 14-3-3 eta, human 14-3-3 gamma, human 14-3-3 sigma, and human 14-3-3 tau protein.
- Clone Name
- AT4F8
- Host
- Mouse
- Clonality
- Monoclonal
- Conjugation
- Unconjugated
- Isotype
- IgG2b
- Antigen Species
- Human
- Purification
- Protein A purified
- Concentration
- 1 mg/ml (Please refer to the vial label for the specific concentration.)
- Shipping Temperature
- 4
- Immunogen
- The clone AT4F8 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-5 epsiilon protein.
- Buffer
- PBS (pH7.4), 10% Glycerol
- Gene ID
- 7531
- Fullname
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
- Uniport ID
- P62258
- Calculated MW
- 29
- Reactivity
- Human
Mouse
- Form
- Liquid
- Product Type
- Primary Antibodies
- Product Link
- https://www.genetex.com/Product/Detail/14-3-3-epsilon-antibody-AT4F8/GTX57563