![MDM2 antibody [SMP14]](https://www.axilscientific.com/49595-superlarge_default/mdm2-antibody-smp14-.jpg)
MDM2 antibody [SMP14]
GTX70278
- Brand
- GeneTex
- Application
- IHC (Resin sections)
IHC-Fr
IHC-P
IP
WB
- Storage Conditions
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- Note
- For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
- Synonyms
- MDM2 proto-oncogene , ACTFS , HDMX , hdm2
- Background
- This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
- Clone Name
- SMP14
- Host
- Mouse
- Clonality
- Monoclonal
- Conjugation
- Unconjugated
- Isotype
- IgG1
- Antigen Species
- Human
- Positive Control
- HepG2 , HepG2 (starvation for 16 hr, and 1 μM Staurosporine treatment for 24 hr) ,
- Purification
- Protein G purified
- Concentration
- 1.0 mg/ml (Please refer to the vial label for the specific concentration.)
- Shipping Temperature
- 4
- Immunogen
- Synthetic peptide, CSRPSTSSRRRAISE, corresponding to amino acids 154-167 of human MDM2
- Buffer
- PBS
- Gene ID
- 4193
- Fullname
- MDM2 proto-oncogene
- Uniport ID
- Q00987
- Calculated MW
- 55
- Reactivity
- Human
Mouse
- Form
- Liquid
- Product Type
- Primary Antibodies
- Product Link
- https://www.genetex.com/Product/Detail/MDM2-antibody-SMP14/GTX70278