Myelin basic protein antibody
GTX133108-S
- Brand
- GeneTex
- Application
- ICC/IF
IHC
IHC (Free Floating)
IHC-Fr
IHC-P
WB
- Storage Conditions
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- Note
- For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
- Synonyms
- myelin basic protein , C76307 , Hmbpr , R75289 , golli-mbp , jve , mld , shi
- Background
- The protein encoded by the classic Mbp gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, Mbp-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long Mbp gene (otherwise called "Golli-Mbp") that contains 3 additional exons located upstream of the classic Mbp exons. Alternative splicing from the Golli and the Mbp transcription start sites gives rise to 2 sets of Mbp-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-Mbp, spliced in-frame to 1 or more Mbp exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to Mbp aa sequence. The second family of transcripts contain only Mbp exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the Mbp transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. Mutation of the Mbp gene is associated with the 'shiverer' and 'myelin deficient' phenotypes in mouse. [provided by RefSeq, Jul 2008]
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugation
- Unconjugated
- Isotype
- IgG
- Antigen Species
- Mouse
- Positive Control
- mouse brain , rat brain
- Purification
- Purified by antigen-affinity chromatography.
- Concentration
- 1.36 mg/ml (Please refer to the vial label for the specific concentration.)
- Shipping Temperature
- 4
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse Myelin basic Protein. The exact sequence is proprietary.
- Buffer
- 1XPBS (pH7), 20% Glycerol
- Gene ID
- 17196
- Fullname
- myelin basic protein
- Uniport ID
- P04370
- Calculated MW
- 27
- Application Note
- WB: 1:5000-1:10000. ICC/IF: Assay dependent. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IHC: Assay dependent. IHC (Free Floating): Assay dependent. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Reactivity
- Human
Mouse
Rat
- Form
- Liquid
- Product Type
- Primary Antibodies
- Product Link
- https://www.genetex.com/Product/Detail/Myelin-basic-protein-antibody/GTX133108
Product Information: https://www.genetex.com/Product/Detail/Myelin-basic-protein-antibody/GTX133108
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