GTX00492-00
- Brand
- GeneTex
- Application
- FACS
ICC/IF
IHC-Fr
IHC-P
IP
- Storage Conditions
- Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
- Note
- For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
- Synonyms
- ALPS5 , CD , CD152 , CELIAC3 , CTLA4 , GRD4 , GSE , IDDM12 , cytotoxic Tlymphocyte associated protein 4 , cytotoxic T-lymphocyte associated protein 4
- Background
- This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
- Clone Name
- BNI3
- Host
- Mouse
- Clonality
- Monoclonal
- Conjugation
- Unconjugated
- Isotype
- IgG2a
- Antigen Species
- Human
- Purification
- Protein A purified
- Concentration
- 1 mg/ml (Please refer to the vial label for the specific concentration.)
- Shipping Temperature
- 4
- Immunogen
- Human CD152-IgG heavy chain fusion protein
- Buffer
- 0.2μm filter-sterilized PBS
- Gene ID
- 1493
- Fullname
- cytotoxic T-lymphocyte associated protein 4
- Uniport ID
- P16410
- Calculated MW
- 25
- Application Note
- ICC/IF: Assay dependent. IHC-P: Assay dependent. IHC-Fr: Assay dependent. FACS: Assay dependent. IP: Assay dependent. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Reactivity
- Human
- Form
- Liquid
- Product Type
- Primary Antibodies
- Product Link
- https://www.genetex.com/Product/Detail/CTLA4-antibody-BNI3-Low-Endotoxin/GTX00492-00