Cytokeratin 8 antibody
GTX110311-S
- Brand
- GeneTex
- Application
- ICC/IF
IHC-P
IHC-Wm
WB
- Storage Conditions
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- Note
- For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
- Synonyms
- keratin 8 , CARD2 , CK-8 , CK8 , CYK8 , K2C8 , K8 , KO
- Background
- This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq]
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugation
- Unconjugated
- Isotype
- IgG
- Antigen Species
- Human
- Positive Control
- HeLa , HepG2 , JC
- Purification
- Purified by antigen-affinity chromatography.
- Concentration
- 0.66 mg/ml (Please refer to the vial label for the specific concentration.)
- Shipping Temperature
- 4
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Cytokeratin 8. The exact sequence is proprietary.
- Buffer
- 1XPBS (pH7), 20% Glycerol
- Gene ID
- 3856
- Fullname
- keratin 8
- Uniport ID
- P05787
- Calculated MW
- 54
- Application Note
- WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Wm: Assay dependent. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Reactivity
- Human
Mouse
Zebrafish
- Form
- Liquid
- 5 Pillars Validation
- KO/KD
- Product Type
- Primary Antibodies
- Product Link
- https://www.genetex.com/Product/Detail/Cytokeratin-8-antibody/GTX110311