GAD67 antibody
GTX101881-S
- Brand
- GeneTex
- Application
- ICC/IF
IHC (Free Floating)
IHC-Fr
IHC-P
WB
- Storage Conditions
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- Note
- For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
- Synonyms
- glutamate decarboxylase 1 , CPSQ1 , GAD , SCP
- Background
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq]
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugation
- Unconjugated
- Isotype
- IgG
- Antigen Species
- Human
- Positive Control
- SK-N-SH , mouse brain , rat brain , human GAD1-transfected 293T
- Purification
- Purified by antigen-affinity chromatography.
- Concentration
- 0.4 mg/ml (Please refer to the vial label for the specific concentration.)
- Shipping Temperature
- 4
- Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human GAD67. The exact sequence is proprietary.
- Buffer
- 1XPBS (pH7), 1% BSA, 20% Glycerol
- Gene ID
- 2571
- Fullname
- glutamate decarboxylase 1
- Uniport ID
- Q99259
- Calculated MW
- 67
- Application Note
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IHC (Free Floating): Assay dependent. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Reactivity
- Human
Mouse
Rat
- Form
- Liquid
- 5 Pillars Validation
- Overexpression
- Product Type
- Primary Antibodies
- Product Link
- https://www.genetex.com/Product/Detail/GAD67-antibody/GTX101881
Product Information: https://www.genetex.com/Product/Detail/GAD67-antibody/GTX101881
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