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Grp78 antibody [N2C1], Internal
GTX102580-S
- Brand
- GeneTex
- Application
- ICC/IF
IHC-P
IP
WB
- Storage Conditions
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- Note
- For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
- Synonyms
- heat shock protein family A (Hsp70) member 5 , BIP , GRP78 , HEL-S-89n , MIF2
- Background
- When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]
- Specificity
- Knockdown/Knockout validation was supported by customer review data.
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugation
- Unconjugated
- Isotype
- IgG
- Antigen Species
- Human
- Positive Control
- 293T , A431 , HeLa , HepG2 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , PC-12 , Rat2
- Purification
- Purified by antigen-affinity chromatography.
- Concentration
- 1.28 mg/ml (Please refer to the vial label for the specific concentration.)
- Shipping Temperature
- 4
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Grp78. The exact sequence is proprietary.
- Buffer
- 1XPBS (pH7), 20% Glycerol
- Gene ID
- 3309
- Fullname
- heat shock protein family A (Hsp70) member 5
- Uniport ID
- P11021
- Calculated MW
- 72
- Application Note
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Reactivity
- Human
Mosquito
Mouse
Rat
- Form
- Liquid
- 5 Pillars Validation
- KO/KD
- Product Type
- Primary Antibodies
- Product Link
- https://www.genetex.com/Product/Detail/Grp78-antibody-N2C1-Internal/GTX102580
Product Information: https://www.genetex.com/Product/Detail/Grp78-antibody-N2C1-Internal/GTX102580
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