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MAP2 antibody [AP-20]

Catalog No.
GTX11268
Pack Size
  • 50 μl
Quantity

* Free Delivery for Orders SGD$250 (excl. GST) & Above.

Specifications
GTX11268
Brand
GeneTex
Application
ICC/IF
IHC-P
WB
Storage Conditions
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Synonyms
microtubule associated protein 2
Background
MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.
Clone Name
AP-20
Host
Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Antigen Species
Bovine
Positive Control
rat cerebral cortex
Purification
Unpurified
Shipping Temperature
4
Immunogen
bovine MAP2
Buffer
Ascites
Gene ID
281294
Fullname
microtubule associated protein 2
Application Note
WB: 1:500. ICC/IF: Assay dependent. IHC-P: Assay dependent. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Reactivity
Bovine
Human
Mouse
Quail
Rat
Xenopus
aquatic salamander
Form
Liquid
Product Type
Primary Antibodies
Product Link
https://www.genetex.com/Product/Detail/MAP2-antibody-AP-20/GTX11268
More Info
Product Information: https://www.genetex.com/Product/Detail/MAP2-antibody-AP-20/GTX11268
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