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Rb (phospho Ser795) antibody [28B5]
GTX00683
- Brand
- GeneTex
- Application
- ELISA
WB
- Storage Conditions
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- Note
- For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
- Synonyms
- RB transcriptional corepressor 1 , OSRC , PPP1R130 , RB , p105-Rb , pRb , pp110
- Background
- The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
- Clone Name
- 28B5
- Host
- Mouse
- Clonality
- Monoclonal
- Conjugation
- Unconjugated
- Isotype
- IgG2a
- Antigen Species
- Human
- Purification
- Purified IgG
- Concentration
- 1 mg/ml (Please refer to the vial label for the specific concentration.)
- Shipping Temperature
- 4
- Immunogen
- A synthetic peptide containing phospho-Ser795 of human Rb
- Buffer
- Filter-sterilized PBS, 50% Glycerol
- Gene ID
- 5925
- Fullname
- RB transcriptional corepressor 1
- Uniport ID
- P06400
- Calculated MW
- 106
- Application Note
- WB: ~1 μg/ml. ELISA: Assay dependent. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Reactivity
- Human
- Form
- Liquid
- 5 Pillars Validation
- Orthogonal
- Product Type
- Primary Antibodies
- Product Link
- https://www.genetex.com/Product/Detail/Rb-phospho-Ser795-antibody-28B5/GTX00683