SEC23A antibody
GTX79203
- Brand
- GeneTex
- Application
- FACS
ICC/IF
IP
WB
- Storage Conditions
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- Note
- For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
- Synonyms
- Sec23 homolog A, coat complex II component
- Background
- Coatomer proteins are involved in regulating transport between the endoplasmic reticulum (ER) and the Golgi complex and in intra-Golgi transport. There exist two coatomer-protein mechanisms (COPI and COPII) and although they have mechanistic parallels, they are molecularly distinct. The COPI coat is comprised of seven subunits (alpha-, beta-, beta'-, gamma-, delta-, epsilon-, and zeta-COP) in a complex called coatomer. Assembly of the coatomer (COPI) onto non-clathrin coated vesicles is regulated by ADP-ribosylation factor (ARF). Vesicle formation, budding, fusion, and disassembly is dependent on GDP-GTP exchange, COPI, and ARF. COPI has been shown to facilitate retrograde intracellular transport from the ER to the Golgi complex. By contrast, COPII facilitates anterograde transport between these subcellular organelles. COPII has been shown to be independently and selectively recruited to the ER relative to COPI subunits. COPII consists of three parts: Sar1p and the two protein complexes, Sec23p-Sec24p and Sec13p-Sec31p.
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugation
- Unconjugated
- Isotype
- IgG
- Antigen Species
- Rat
- Purification
- Purified by antigen-affinity chromatography
- Concentration
- 1 mg/ml (Please refer to the vial label for the specific concentration.)
- Shipping Temperature
- 4
- Immunogen
- Synthetic peptide corresponding to residues M(1) T T Y L E F I Q Q N E E R D G V R (18) C of rat COPII.
- Buffer
- PBS, 1mg/ml BSA
- Gene ID
- 58817
- Fullname
- Sec23 homolog A, coat complex II component
- Reactivity
- Hamster
Human
Mouse
Rat
- Form
- Liquid
- Product Type
- Primary Antibodies
- Product Link
- https://www.genetex.com/Product/Detail/SEC23A-antibody/GTX79203