Qkine
Based at Murdoch House in Cambridge, Qkine manufactures high-purity, animal-free growth factors, cytokines, and other complex proteins for life science applications including stem cell and organoid culture.
Qkine combines proprietary production processes with protein engineering technology to tackle fundamental biological, quality, and scale-up challenges.
Qkine's goal is to provide the highest purity, bioactive proteins for research and bio-manufacturing to best support our customers and maximize the impact of their science.
More information at https://qkine.com.
Qkine
Human LIF (leukemia inhibitory factor) protein suppresses the differentiation of embryonic stem cells (ESCs) and is widely used in ESC and iPSC culture. Human LIF can be used in the maintenance of both murine and...
Qkine
Human PDGF-AA (platelet derived growth factor AA) protein is a homodimer of PDGF-A peptide chains. This protein is a potent mitogen involved in embryogenesis. PDGF-AA is commonly used to differentiate human...
Qkine
Human/mouse/rat activin A protein is a member of the TGFβ superfamily of growth factors used for maintenance of pluripotency in many induced pluripotent stem cell (iPSC) and embryonic stem cell (ESC) lines, and to...
Qkine
Human FGF-9 protein is a member of the fibroblast growth factor (FGF) family, FGF-9 is involved in many developmental processes including neural and skeletal development. Recombinant FGF-9 is used frequently in the...
Qkine
R-spondin 1 LR5 protein is engineered to act as a high affinity ligand for the LGR5 receptor. In epithelial tissues LGR5 marks the stem cell population. This engineered protein, R-spondin 1 LR5, activates wnt...
Qkine
Human R-spondin 3 protein potentiates Wnt signalling in and has been shown to function in crypt regeneration in the intestine and control stem cell and progenitor cell behaviour during kidney development. R-spondin 3...
Qkine
Mouse Noggin supports growth of organoids derived from mouse epithelial tissues and stem cell differentiation. Noggin protein is a bone morphogenetic protein (BMP) family antagonist used in the culture of intestinal,...
Qkine
Human Gremlin 1 protein is a BMP-inhibitor present in the natural intestinal niche and provides an alternative to Noggin for optimisation of intestinal organoid culture and iPSC differentiation.
Qk015 has been...
Qkine
Human/mouse/rat activin A PLUS protein is an optimised biologically active truncation of the mature domain of human Activin A protein. The EC50 and activity in stem cell culture of activin A PLUS is equivalent to the...
Qkine
Human FGF-4 protein is used for the proliferation and differentiation of embryonic and induced-pluripotent and tissue (mesenchymal) stem cells and promotes neural stem cell proliferation. FGF-4 is an important...
Qkine
Human/rat/porcine/bovine FGF-10 protein promotes lung organoid formation and induces branching morphology. FGF-10 protein is used widely in organoid culture, embryonic stem cell (ESC) and induced-pluripotent stem...
Qkine
Recombinant follistatin-resistant activin A (FRACTA) has been engineered to prevent binding to the natural inhibitor, follistatin. Activin A activity protein is regulated in vivo by follistatin, a high-affinity...
Qkine
Human Noggin supports growth of organoids derived from epithelial tissues and iPSC and ESC differentiation. Noggin protein is a bone morphogenetic protein (BMP) family antagonist used in the culture of intestinal,...
Qkine
Recombinant human HGF (NK1) protein is a potent, high purity NK1 isoform of human hepatocyte growth factor (HGF) that promotes efficient differentiation of human iPSCs to hepatocyte-like cells at just 10 ng/ml with...
Qkine
Mouse LIF (murine leukemia inhibitory factor) protein supports the derivation, propagation and expansion of mouse embryonic stem cells (ESC), and maintenance of pluripotency. LIF protein increases the robustness of...
Qkine
Human IGF-1 (IGF-I), insulin-like growth factor 1, protein is used in the maintenance of human pluripotent stem cells and is necessary for cell growth in the absence of insulin1. IGF-1 promotes the proliferation of...
Qkine
Human NRG-1 (Neuregulin 1) protein is frequently used in the maintenance of human pluripotent stem cells. In addition to its widespread use in stem cell culture media, NRG-1 (also known as Heregulin-β1 , HRG-1) has...
Qkine
Human OSM (oncostatin M) protein is used in the differentiation of human pluripotent stem cells into hepatocyte-like cells. OSM also plays roles in osteogenesis and neurogenesis, and is an important regulator of the...
Qkine
Human Glial cell line-derived neurotrophic factor (GDNF) protein supports the maintenance and differentiation of numerous types of neurons including dopaminergic neurons. GDNF is used to differentiate human...
Qkine
Human BDNF (brain-derived neurotrophic factor) protein is an important regulator of neural development, maintenance and function. Used in differentiation of human pluripotent stem cell-derived neural progenitors to...