FectoVIR®-AAV
AAVs are becoming the leading viral vector in the development of gene-based advanced therapy medicinal products (ATMPs). Their success is due to their intrinsic properties: they are primarily non-integrating as they persist within cells as episomes, and have a broad tropism with eleven serotypes that have the ability to infect specific cell types. A major challenge today is manufacturing sufficient quantities of AAV in order to treat larger groups of patients. FectoVIR®-AAV is a novel class of animal free transfection reagent specifically developed for industrial scale production of recombinant AAV (rAAV) viral vectors in suspension HEK-293 cell types. FectoVIR®-AAV transfection reagent guarantees higher rAAV viral titers, improved flexibility and scalability for industrial scale manufacturing.
- Brand
- Polyplus-transfection
- Application
- Recombinant AAV virus production in suspension cells
- Previous Catalog No
- 120-01L
- Molecule Delivered
- Plasmid DNA and co-delivery of several plasmid DNA
- Cell Types
- Mammalian producer cell lines (HEK-293, HEK-293 derivatives) grown in suspension cultures
- Virus Types
- Adeno-Associated Viruses (AAV)
- No. of Transfections
- 100 mL of FectoVIR®-AAV transfection reagent is sufficient to transfect on average 50 L of cell culture
- GMP
- FectoVIR®-AAV GMP available
- Storage
- Store FectoVIR®-AAV at 5 °C ± 3°C.
- Provided with
- Protocol
Certificate of Analysis
Certificate of Origin
Non-Hazardous Product Statement