Goat anti-ATM Antibody Agarose Immobilized
Brand:
S300-135
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Goat
- Conjugation
- Agarose Immobilized
- Immunogen
- between 1750 and 1800
- Buffer
- Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- ATM
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- AT mutated, A-T mutated, AT1, ATA, ataxia telangiectasia mutated, ATC, ATD, ATDC, ATE, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
- Format
- Whole IgG
- Product Type
- Immobilized Immunochemicals
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 41116127
- Immunoprecipitation (IP)
- 15 - 25 µl of gel slurry per 0.1 to 1 mg of protein lysate or extract
- Target Sentence
- Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4.
- Product Link
- http://www.bethyl.com/product/S300-135
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