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Mouse anti-CD68 Recombinant Monoclonal Antibody, Purified [KP-1]
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Brand:
A500-018A-T
- Brand
- Bethyl Laboratories
- Application
- F
IHC
IHC-IF
mIF
- Storage Conditions
- 2 - 8° C
- Host
- Mouse
- Conjugation
- Unconjugated
- Immunogen
- Lysosomal fraction of human lung macrophages
- Buffer
- Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CD68
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- CD antigen CD68, CD68 antigen, GP110, LAMP4, macrophage antigen CD68, macrosialin, SCARD1, scavenger receptor class D, member 1
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
- Immunohistochemistry-Immunofluoresence (IHC-IF)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
- Flow Cytometry (F)
- 2 µl per 1 X 10^6 cells
- Target Sentence
- CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins.CD68 is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages [taken from NCBI Entrez Gene (Gene ID: 968)].
- Product Link
- http://www.bethyl.com/product/A500-018A
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