Rabbit anti-A20 Antibody, Affinity Purified
Brand:
A302-633A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 525 and 575
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- A20
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- A20, AISBL, OTU domain-containing protein 7C, OTUD7C, putative DNA-binding protein A20, TNF alpha-induced protein 3, TNFA1P2, tumor necrosis factor alpha-induced protein 3, tumor necrosis factor inducible protein A20, tumor necrosis factor, alpha induced protein 3, zinc finger protein A20
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- Zinc-finger protein A20 was identified as a transcript that was rapidly induced by tumor-necrosis factor alpha (TNF-alpha). A20 is an essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Upon TNF stimulation, A20 deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P21580].
- Product Link
- http://www.bethyl.com/product/A302-633A
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