Rabbit anti-ACC1/ACC-alpha Antibody, Affinity Purified
Brand:
A300-987A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 2333 and C-term
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- ACC1/ACC-alpha
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- ACAC, ACACAD, ACC, ACC1, ACCA, ACC-alpha, acetyl-CoA carboxylase 1, acetyl-Coenzyme A carboxylase alpha, Biotin carboxylase
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Sheep and Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- Not recommended. Use rabbit anti-ACC1/ACC-alpha antibody A300-986A.
- Target Sentence
- ACC1/ACC-alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA in the enzymatic pathway of long-chain fatty-acid synthesis. ACC1/ACC-alpha has been identified as a partner of BRCA1. Through this interaction, ACC1/ACC-alpha may contribute to the tumor suppressor activity of BRCA1 as demonstrated by the finding that disruption of this interaction increases lipid synthesis in mammary epithelial cells. In this context, lipogenesis has been closely linked to tumorigenesis and ACC1/ACC-alpha has been found to be highly expressed in human breast carcinomas.
- Product Link
- http://www.bethyl.com/product/A300-987A
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