Rabbit anti-Alsin Antibody, Affinity Purified
Brand:
A304-511A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1250 and 1300
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- Alsin
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- ALS2CR6, alsin, ALSJ, amyotrophic lateral sclerosis 2 (juvenile), amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, amyotrophic lateral sclerosis 2 protein, IAHSP, PLSJ
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- Not recommended
- Target Sentence
- Alsin contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. Alsin localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in the gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis [taken from NCBI Entrez Gene (Gene ID: 57679)].
- Product Link
- http://www.bethyl.com/product/A304-511A
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