Rabbit anti-ARAP3 Antibody, Affinity Purified
Brand:
A305-644A-M
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 1200 and 1250
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- ARAP3
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- Arf and Rho GAP adapter protein 3, arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3, centaurin-delta-3, CENTD3, Cnt-d3, DRAG1, phosphoinositide binding protein, PtdIns(3,4,5)P3-binding protein
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A305-644A-T has not performed satisfactorily when used for WB of ARAP3 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of ARAP3.
- Immunoprecipitation (IP)
- 8 - 15 µl/mg lysate
- Target Sentence
- ARAP3 is a phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. It is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. It can also be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. ARAP3 acts on ARF6, RAC1, RHOA and CDC42. ARAP3 plays a role in the internalization of anthrax toxin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WWN8].
- Product Link
- http://www.bethyl.com/product/A305-644A-T