A300-916A-M
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 870 and C-term
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- BCAS3
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- BCAS4/BCAS3 fusion, breast carcinoma amplified sequence 4/3 fusion protein, breast carcinoma-amplified sequence 3, GAOB1, MAAB, metastasis associated antigen of breast cancer, protein Maab1, Rudhira
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 or Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
- Target Sentence
- Breast cancer amplified sequence 3 (BCAS3) was identified as a gene overexpressed and amplified in breast cancer cell lines. BCAS3 expression has been shown to be regulated by estrogen receptor alpha (ER alpha) and its coregulator PELP1 (proline-, glutamic acid-, and leucine-rich protein 1). BCAS3 has also been demonstrated to act as a coactivator of ER alpha activity in breast cancer cells and associate with the histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor).
- Product Link
- http://www.bethyl.com/product/A300-916A