A304-612A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1 and 50
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- BLOC1S3
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- biogenesis of lysosome-related organelles complex 1 subunit 3, biogenesis of lysosome-related organelles complex-1, subunit 3, BLOC-1 subunit 3, BLOS3, HPS8, reduced pigmentation, mouse, homolog of, RP
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- BLOC1S3 is a component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. It plays a role in intracellular vesicle trafficking [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6QNY0].
- Product Link
- http://www.bethyl.com/product/A304-612A