Rabbit anti-BubR1 IHC Antibody, Affinity Purified
Brand:
IHC-00498-T
- Brand
- Bethyl Laboratories
- Application
- IHC
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1 and 50
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- BubR1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- Bub1A, BUB1B, mitotic checkpoint serine/threonine kinase, BUB1beta, BUBR1, budding uninhibited by benzimidazoles 1 homolog beta, hBUBR1, MAD3/BUB1-related protein kinase, MAD3L, mitotic checkpoint kinase MAD3L, mitotic checkpoint serine/threonine-protein kinase BUB1 beta, MVA1, Protein SSK1, SSK1
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500
- Target Sentence
- BubR1 is cell cycle checkpoint kinase and component of the spindle checkpoint machinery. BubR1 and other spindle checkpoint proteins ensure that segregation does not proceed until all replicated chromatids are associated with a functional bipolar spindle. BubR1 is part of the mitotic checkpoint complex that also includes Bub3, Mad2, and Cdc20. In this trimer BubR1 functions to inhibit the anaphase promoting complex (APC) that promotes chromosome segregation. BubR1 is suggested to be a paralog of Bub1.
- Product Link
- http://www.bethyl.com/product/IHC-00498-T
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