Rabbit anti-cAbl IHC Antibody, affinity purified
Brand:
IHC-00405-T
- Brand
- Bethyl Laboratories
- Application
- ICC
ICC-IF
IHC
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 850 and 900
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- cAbl
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, ABL, bcr/abl, bcr/c-abl oncogene protein, c-ABL, c-abl oncogene 1, receptor tyrosine kinase, c-ABL1, CHDSKM, JTK7, p150, proto-oncogene c-Abl, proto-oncogene tyrosine-protein kinase ABL1, tyrosine-protein kinase ABL1, v-abl, v-abl Abelson murine leukemia viral oncogene homolog 1
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500
- Immunocytochemistry (ICC)
- 1:100 - 1:500
- Immunocytochemistry-Immunofluoresence (ICC-IF)
- 1:50 - 1:500
- Target Sentence
- c-Abl is the human cellular homolog of a the v-Abl viral oncogene. v-Abl was originally discovered as a mouse cell-derived sequence in the genome of the Abelson murine leukemia virus (A-MuLV), a transforming retrovirus isolated by the laboratory of Dr. H.T. Abelson. c-Abl is a tyrosine kinase from the Src-family of tyrosine kinases that localizes to both the cytoplasm and nucleus. It bears an SH2 (src-homology 2) and SH3 (src-homology 3) domain responsible for mediating c-Abl protein-protein interactions. c-Abl is implicated to play a role in multiple cellular processes such as cell cycle checkpoint signaling, apoptosis, cell differentiation, cell adhesion, and transcriptional regulation. Chromosomal translocations involving the c-Abl gene are associated with human leukemias.
- Product Link
- http://www.bethyl.com/product/IHC-00405-T
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