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Rabbit anti-Caldesmon Antibody, Affinity Purified

Catalog No.
A304-164A-T
Pack Size
  • 100 µl (1000 µg/ml)
  • 10 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A304-164A-T
Brand
Bethyl Laboratories
Application
IHC
IP
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 675 and 725
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
Caldesmon
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
caldesmon, CDM, HCAD, H-CAD, LCAD, L-CAD, NAG22, testis secretory sperm-binding protein Li 227n
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Rat, Chicken and Turkey
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
Not recommended. Use rabbit anti-Caldesmon antibody A304-165A.
Immunoprecipitation (IP)
2 - 10 µg/mg lysate
Immunohistochemistry (IHC)
1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Sentence
Caldesmon is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of caldesmon possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction [taken from NCBI Entrez Gene (Gene ID: 800)].
Product Link
http://www.bethyl.com/product/A304-164A
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