IHC-00045-T
- Brand
- Bethyl Laboratories
- Application
- IHC
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 550 and C-term
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CARM1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- Coactivator-associated arginine methyltransferase 1, histone-arginine methyltransferase CARM1, PRMT4, protein arginine N-methyltransferase 4
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500
- Target Sentence
- Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). CARM1 (coactivator-associated arginine methyltransferase 1), also known as PRMT4, has been shown to interact with and methylate RNA splicing factors such as CA150 that link transcription to splicing. In this context, CARM1 may be involved in spinal muscular atrophy pathogenesis. CARM1 has also been found to be a coactivator of the NFKappaB transcription factor and the androgen receptor.
- Product Link
- http://www.bethyl.com/product/IHC-00045-T