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Rabbit anti-CASC3 Antibody, Affinity Purified

Catalog No.
A302-472A-M
Pack Size
  • 20 µl (2 blots)
  • 100 µl (10 blots)
  • 100 µl (200 µg/ml)
Quantity
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Brand:
Specifications
A302-472A-M
Brand
Bethyl Laboratories
Application
IHC
IP
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 653 and 703
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human
Target
CASC3
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
barentsz, BTZ, cancer susceptibility 3, cancer susceptibility candidate 3, cancer susceptibility candidate gene 3 protein, metastatic lymph node 51, metastatic lymph node gene 51 protein, MLN 51, MLN51, protein barentsz, protein CASC3
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Bovine
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:2,000 - 1:10,000
Immunoprecipitation (IP)
2 - 5 µg/mg lysate
Immunohistochemistry (IHC)
1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Sentence
Cancer susceptibility candidate gene 3 protein (CASC3) is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. CASC3 is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles [taken from NCBI Entrez Gene (GeneID: 22794)].
Product Link
http://www.bethyl.com/product/A302-472A
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