Rabbit anti-CAV1 Antibody, Affinity Purified
Brand:
A305-901A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CAV1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- BSCL3, caveolin 1, caveolae protein, 22kDa, caveolin-1, cell growth-inhibiting protein 32, CGL3, LCCNS, MSTP085, PPH3, VIP21
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Sheep, Bovine, Horse, Rabbit, Pig, Cat, Orangutan, Gorilla and Chimpanzee
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1000
- Immunoprecipitation (IP)
- 20-40 µl/mg lysate
- Target Sentence
- CAV1 acts as a scaffolding protein within caveolar membranes and forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. CAV1 also mediates the recruitment of CAVIN proteins to the caveolae and interacts directly with G-protein alpha subunits and can functionally regulate their activity. CAV1 is also thought to be involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation, as its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q03135].
- Product Link
- http://www.bethyl.com/product/A305-901A-T