Rabbit anti-CBFA2T2 Antibody, Affinity Purified
Brand:
A303-593A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 554 and 604
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CBFA2T2
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- core-binding factor, runt domain, alpha subunit 2; translocated to, 2, EHT, ETO homolog on chromosome 20, ETO homologous on chromosome 20, MTG8-like protein, MTG8-related protein 1, MTGR1, myeloid translocation gene-related protein 1, myeloid translocation-related protein 1, p85, protein CBFA2T2, ZMYND3
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- CBFA2T2 may function in a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). CBFA2T2 may thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. CBF2T2 may be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O43439].
- Product Link
- http://www.bethyl.com/product/A303-593A
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