Rabbit anti-CBFA2T3 Antibody, Affinity Purified
Brand:
A303-616A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 603 and 653
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CBFA2T3
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- core-binding factor, runt domain, alpha subunit 2; translocated to, 3, ETO2, hMTG16, MTG16, MTG8-related gene 2, MTG8-related protein 2, MTGR2, myeloid translocation gene 8 and 16b, myeloid translocation gene on chromosome 16 protein, protein CBFA2T3, RUNX1T3, zinc finger MYND domain-containing protein 4, ZMYND4
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- CBFA2T3 (core-binding factor, runt domain, alpha subunit 2; translocated to, 3) is a member of the myeloid translocation gene family which interacts with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of the CBFA2T3 gene. This gene is also a putative breast tumor suppressor. [taken from NCBI Entrez Gene (Gene ID: 863)].
- Product Link
- http://www.bethyl.com/product/A303-616A
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