Rabbit anti-Cbl-b Antibody, Affinity Purified
Brand:
A302-903A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 932 and 982
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- Cbl-b
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- Cas-Br-M (murine) ecotropic retroviral transforming sequence b, casitas B-lineage lymphoma proto-oncogene b, Cbl proto-oncogene B, E3 ubiquitin protein ligase, Cbl proto-oncogene, E3 ubiquitin protein ligase B, Cbl-b, E3 ubiquitin-protein ligase CBL-B, Nbla00127, RING finger protein 56, RING-type E3 ubiquitin transferase CBL-B, RNF56, SH3-binding protein CBL-B, signal transduction protein CBL-B
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- Cbl-b is an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Cbl-b negatively regulates TCR (T-cell receptor), BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q13191].
- Product Link
- http://www.bethyl.com/product/A302-903A
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