A300-554A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 900 and 950
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CDK5RAP2
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- C48, CDK5 activator-binding protein C48, CDK5 regulatory subunit-associated protein 2, centrosomal protein 215 kDa, Centrosome-associated protein 215, centrosomin, Cep215, MCPH3
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Chimpanzee
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,500 - 1:15,000
- Immunoprecipitation (IP)
- 3 - 5 µg/mg lysate
- Target Sentence
- Mutations in CDK5RAP2 (CDK5 regulatory subunit-associated protein 2) have been linked to microcephaly. CDK5RAP2 may be involved in centrosome directed production of microtubules and mitotic spindle formation during neural cell division. CDK5RAP2 associates with the activating subunit of Cdk5, p25NCK5A. Cdk5 is a brain specific cyclin-dependent kinase important to mammalian brain development.
- Product Link
- http://www.bethyl.com/product/A300-554A