Rabbit anti-CDK5RAP3 Antibody, Affinity Purified
Brand:
A300-871A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 450 and C-term
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CDK5RAP3
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- C53, CDK5 activator-binding protein C53, CDK5 regulatory subunit associated protein IC53-2, CDK5 regulatory subunit-associated protein 3, HSF-27, IC53, ischemic heart CDK5 activator-binding protein C53, LXXLL/leucine-zipper-containing ARFbinding protein, LXXLL/leucine-zipper-containing ARF-binding protein, LZAP, MST016, OK/SW-cl.114, PP1553, Protein HSF-27
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- CDK5RAP3 (CDK5 regulatory subunit-associated protein 3) was identified as a protein that associates with the activating subunit of Cdk5, p25NCK5A. Cdk5 is a brain specific cyclin-dependent kinase important to mammalian brain development; however CDK5RAP3 appears to be widely expressed in human tissues. CDK5RAP3 appears to exhibit functions that extend beyond its association with Cdk5. CDK5RAP3 is involved in modulating the G2/M DNA damage checkpoint and can associate with and regulate the Cdk1-cyclin B1 complex. CDK5RAP3 has also been demonstrated to interact with and regulate the tumor suppressor ARF (alternative reading frame) to further play a role in cell cycle progression.
- Product Link
- http://www.bethyl.com/product/A300-871A
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