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Rabbit anti-CDK7 Recombinant Monoclonal Antibody [BL-80-5D4]
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Brand:
A700-006-T
- Brand
- Bethyl Laboratories
- Application
- F
ICC
IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 300 and 346 (C-term)
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CDK7
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- 39 KDa protein kinase, CAK, CAK1, CDK-activating kinase 1, CDKN7, cell division protein kinase 7, cyclin-dependent kinase 7, cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase), HCAK, homolog of Xenopus MO15 Cdk-activating kinase, kinase subunit of CAK, MO15, p39 Mo15, p39MO15, serine/threonine kinase stk1, serine/threonine protein kinase 1, serine/threonine protein kinase MO15, Serine/threonine-protein kinase 1, STK1, TFIIH basal transcription factor complex kinase subunit
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1000
- Immunoprecipitation (IP)
- 20 µl/0.5 mg lysate
- Immunohistochemistry (IHC)
- 1:25 - 1:100. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Immunocytochemistry (ICC)
- 1:50 - 1:200. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Flow Cytometry (F)
- 1 µl per 1 X 10^6 cells
- Target Sentence
- Cyclin-dependent kinase 7 (CDK7) is a member of the CDK family of protein kinases that regulate cell cycle progression. CDK7 is the catalytic subunit in a trimeric complex with cyclin H and MAT1 that functions as a Cdk-activating kinase (CAK). CDK7 activates the kinase activities of CDK1, CDK2, CDK4, and CDK6 by threonine phosphorylation. In addition to its cell cycle function CDK7 has also been found to be an essential component of the transcription factor TFIIH. Several substrates of CDK7 are involved in transcription, further indicating a role in transcription.
- Product Link
- http://www.bethyl.com/product/A700-006