A304-433A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 2964 and 3014
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CELSR1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- ADGRC1, adhesion G protein-coupled receptor C1, cadherin EGF LAG seven-pass G-type receptor 1, cadherin family member 9, cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila), CDHF9, flamingo homolog 2, FMI2, HFMI2, ME2, protocadherin flamingo 2
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000 - 1:5,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions.CELSR1 is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis [taken from NCBI Entrez Gene (Gene ID: 9620)].
- Product Link
- http://www.bethyl.com/product/A304-433A