Rabbit anti-CYFIP1 Antibody, Affinity Purified
Brand:
A302-996A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1203 and 1253
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- CYFIP1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- cytoplasmic FMR1-interacting protein 1, cytoplasmic FMRP interacting protein 1, P140SRA-1, selective hybridizing clone, SHYC, specifically Rac1-associated protein 1, SRA1, SRA-1
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000 - 1:5,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- Cytoplasmic FMR1-interacting protein 1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA. CYFIP1 is involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. CYFIP1 may act as an invasion suppressor in cancers [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q7L576].
- Product Link
- http://www.bethyl.com/product/A302-996A
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