A303-640A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 200 and 250
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- DCP1B
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- DCP1, DCP1 decapping enzyme homolog B, decapping enzyme hDcp1b, mRNA-decapping enzyme 1B
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A303-640A has not performed satisfactorily when used for WB of DCP1B in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of DCP1B.
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- mRNA-decapping enzyme 1B (DCP1B) may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8IZD4].
- Product Link
- http://www.bethyl.com/product/A303-640A