Rabbit anti-DDX26/DICE1 IHC Antibody, Affinity Purified
Brand:
IHC-00602-T
- Brand
- Bethyl Laboratories
- Application
- IHC
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 750 and 800
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- DDX26/DICE1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- DBI-1, DDX26, DDX26A, DEAD box protein, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26, DICE1, HDB, INT6, integrator complex subunit 6, Notchl2, Protein DDX26, protein deleted in cancer 1, RNA helicase HDB
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500
- Target Sentence
- DDX26/DICE1 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX26/DICE1 is a subunit of the integrator complex involved in 3’-end processing of snRNAs. DDX26/DICE1 is implicated as a tumor suppressor, and its ectopic expression has been shown to inhibit tumor cell growth. Alternative names for DDX26/DICE1 include integrator complex subunit 6, Int6, protein deleted in cancer 1, protein DDX26, DBI-1, deleted in cancer 1, INTS6, DDX26A, HDB, Nochl2, and DKFZP434B105.
- Product Link
- http://www.bethyl.com/product/IHC-00602-T
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