Rabbit anti-DEC1 Antibody, Affinity Purified
Brand:
A300-649A-M
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 350 and C-term
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- DEC1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- basic helix-loop-helix domain containing, class B, 2, BHLHB2, bHLHe40, class B basic helix-loop-helix protein 2, class E basic helix-loop-helix protein 40, Clast5, DEC1, differentially expressed in chondrocytes 1, differentially expressed in chondrocytes protein 1, differentiated embryo chondrocyte expressed gene 1, enhancer-of-split and hairy-related protein 2, HLHB2, SHARP2, SHARP-2, stimulated by retinoic acid gene 13 protein, STRA13, Stra14
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
- Target Sentence
- DEC1 is a basic helix-loop-helix transcription factor that appears to play a role in cell differentiation, proliferation, apoptosis, and the circadian rhythm. DEC1 is able to promote chondrogenic and osteogenic differentiation in mesenchymal stem cells by activating transcription of bone-related genes. When it is overexpressed in cells it can suppress apoptosis by blocking caspase activation and inducing transcription of survivin. DEC1 has also been found to play a role mammalian in circadian rhythm as a suppressor of the CLOCK/BMAL1 promoter.
- Product Link
- http://www.bethyl.com/product/A300-649A
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