Rabbit anti-Derlin-1 Antibody, Affinity Purified
Brand:
A302-849A-M
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 201 and 251
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- Derlin-1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- degradation in endoplasmic reticulum protein 1, DER1, DER-1, Der1-like domain family, member 1, Der1-like protein 1, derlin-1, DERtrin-1
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Bovine and Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Target Sentence
- Derlin-1 (Degradation in endoplasmic reticulum protein 1) is a functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Derlin-1 may act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BUN8].
- Product Link
- http://www.bethyl.com/product/A302-849A
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