A301-638A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 100 and 150
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- DOCK11
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- ACG, Activated Cdc42-associated guanine nucleotide exchange factor, Activated Cdc42-associated guanine nucleotide exchange factor, ACG, bB128O4.1, bB128O4.1.1 (novel protein), dedicator of cytokinesis protein 11, ZIZ2, zizimin2, zizimin-2
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A301-638A has not performed satisfactorily when used for WB of DOCK11 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of DOCK11.
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- DOCK11 (dedicator of cytokinesis 11) is also known as zizimin-2. It is a DOCK180-related guanine nucleotide exchange factor (GEF) for the small GTPase, Cdc42. As a GEF, DOCK11 functions to catalyze the dissociation of GDP from the GTPase. Dissociation of GDP allows an exchange for GTP and subsequent downstream signaling by the GTPase.
- Product Link
- http://www.bethyl.com/product/A301-638A