A301-287A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1715 and 1765
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- DOCK180
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- 180 kDa protein downstream of CRK, ced5, dedicator of cytokinesis protein 1, DOCK180, DOwnstream of CrK
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. Use rabbit anti-DOCK180 antibody A301-288A.
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- DOCK80 is a non-conventional Rho-guanine nucleotide exchange factor (Rho-GEF) that functions to activate the small GTPases Rac and Cdc42. It is a member of the CZH (CDM-zizimin homology) family of proteins that contain two highly conserved domains, CZH1 and CZH2. Dock180 functions to activate Rac and regulate cell adhesion, cell spreading, migration and phagocytosis.
- Product Link
- http://www.bethyl.com/product/A301-287A