Rabbit anti-DUSP12 Antibody, Affinity Purified
Brand:
A305-588A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1 and 50
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- DUSP12
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- dual specificity protein phosphatase 12, dual specificity tyrosine phosphatase YVH1, DUSP1, serine/threonine specific protein phosphatase, YVH1, YVH1 protein-tyrosine phosphatase ortholog
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1000
- Immunoprecipitation (IP)
- The antibody contained within A305-588A-T has been qualified for use in immunoprecipitation; however, we recommend purchasing the larger volume found as product A305-588A-M.
- Target Sentence
- Dual specificity protein phosphatase 12 (DUSP12) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain [taken from NCBI Entrez Gene (Gene ID: 11266)].
- Product Link
- http://www.bethyl.com/product/A305-588A-T