A304-819A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1 and 50
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- DYNLT1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- CW-1, dynein light chain Tctex-type 1, Protein CW-1, T-complex testis-specific protein 1 homolog, t-complex-associated-testis-expressed 1-like 1, TCTEL1, tctex-1
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:10,000 - 1:25,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- DYNLT1 is a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. DYNLT1 regulates the length of primary cilia which are sensory organelles found on the surface of cells. It interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. DYNLT1 protein also interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation [taken from NCBI Entrez Gene (Gene ID: 6993)].
- Product Link
- http://www.bethyl.com/product/A304-819A