Rabbit anti-DYRK1A Antibody, Affinity Purified
Brand:
A303-802A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 713 and 763
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- DYRK1A
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, dual specificity tyrosine-phosphorylation-regulated kinase 1A, dual specificity YAK1-related kinase, DYRK, DYRK1, hMNB, HP86, MNB, mnb protein kinase homolog hp86, MNB/DYRK protein kinase, MNBH, MRD7, protein kinase minibrain homolog, serine/threonine kinase MNB, serine/threonine-specific protein kinase
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, X. laevis and X. tropicalis
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. DYRK1A contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. DYRK1A may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. The DYRK1A gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome [taken from NCBI Entrez Gene (Gene ID: 5201)].
- Product Link
- http://www.bethyl.com/product/A303-802A
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