Rabbit anti-E2-25K Antibody, Affinity Purified
Brand:
A304-125A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 150 and 200
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- E2-25K
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- E2 ubiquitin-conjugating enzyme K, E2(25K), E2-25K, HIP2, HIP-2, huntingtin-interacting protein 2, HYPG, LIG, UBC1, ubiquitin carrier protein, ubiquitin conjugating enzyme E2K, ubiquitin-conjugating enzyme E2 K, ubiquitin-conjugating enzyme E2(25K), ubiquitin-conjugating enzyme E2-25 KDA, Ubiquitin-conjugating enzyme E2-25K, ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast), ubiquitin-protein ligase
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000 - 1:5,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Ubiquitin-conjugating enzyme E2-25 kDa (E2-25K) belongs to the ubiquitin-conjugating enzyme family. E2-25K interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation [taken from NCBI Entrez Gene (Gene ID: 3093)].
- Product Link
- http://www.bethyl.com/product/A304-125A
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