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Rabbit anti-EYA3 Antibody, Affinity Purified

Catalog No.
A302-690A-T
Pack Size
  • 100 µl (1000 µg/ml)
  • 10 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A302-690A-T
Brand
Bethyl Laboratories
Application
IP
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 30 and 60
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
EYA3
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
eyes absent 3, eyes absent homolog 3
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
Not recommended. Use rabbit anti-EYA3 antibody A302-689A.
Immunoprecipitation (IP)
2 - 5 µg/mg lysate
Target Sentence
EYA3 (eyes absent homolog 3) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA3 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA3 coactivates SIX1. Together with SIX1 and DACH2 EYA3 seems to be involved in myogenesis. EYA3 may be involved in development of the eye [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99504].
Product Link
http://www.bethyl.com/product/A302-690A
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