Rabbit anti-FAM126A Antibody, Affinity Purified
Brand:
A305-710A-M
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 400 and 450
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- FAM126A
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- down regulated by Ctnnb1, a, down-regulated by CTNNB1 protein A, DRCTNNB1A, HCC, HLD5, HYCC1, hyccin, Protein FAM126A
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A305-710A-T has not performed satisfactorily when used for WB of FAM126A in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of FAM126A.
- Immunoprecipitation (IP)
- 8 - 15 µl/mg lysate
- Target Sentence
- FAM126A is a component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (PubMed:26571211). FAM126A plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P (PubMed:26571211). Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system (PubMed:26571211, PubMed:16951682). FAM126A may also have a role in the beta-catenin/Lef signaling pathway (Probable) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BYI3].
- Product Link
- http://www.bethyl.com/product/A305-710A-T