Rabbit anti-Frizzled-6 Antibody, Affinity Purified
Brand:
A302-963A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 656 and 706
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- Frizzled-6
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- frizzled 6, seven transmembrane spanning receptor, frizzled family receptor 6, frizzled homolog 6, frizzled-6, FZ6, FZ-6, HFZ6, NDNC10, seven transmembrane helix receptor
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A302-963A has not performed satisfactorily when used for WB of Frizzled-6 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Frizzled-6.
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- Frizzled-6 is a receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin, and activation of wnt target genes. In mice, frizzled-6 is critical to B-cell development.
- Product Link
- http://www.bethyl.com/product/A302-963A
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