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Rabbit anti-FUSIP1 IHC Antibody, Affinity Purified

Catalog No.
IHC-00642-T
Pack Size
  • 10 µl (5+ slides)
Quantity
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Brand:
Specifications
IHC-00642-T
Brand
Bethyl Laboratories
Application
IHC
IHC-IF
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 133 and 183
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human
Target
FUSIP1
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
40 kDa SR-repressor protein, FUS-interacting protein (serine-arginine rich) 2, FUS-interacting serine-arginine-rich protein 1, FUSIP1, FUSIP2, neural-salient SR protein, NSSR, PPP1R149, protein phosphatase 1, regulatory subunit 149, serine/arginine-rich splicing factor 10, serine-arginine repressor protein (40 kDa), SFRS13, SFRS13A, splicing factor SRp38, splicing factor, arginine/serine-rich 13, splicing factor, arginine/serine-rich 13A, SR splicing factor 10, SRp38, SRrp40, TASR, TASR1, TASR2, TLS-associated protein TASR, TLS-associated protein with Ser-Arg repeats, TLS-associated protein with SR repeats, TLS-associated serine-arginine protein
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Immunohistochemistry (IHC)
1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)
1:50 - 1:500
Target Sentence
FUSIP1 (FUS-interacting protein 1) was originally identified in a two-hybrid screen for partners of the TLS (translocated in liposarcoma) protein also known as FUS. FUSIP1 is a splicing factor of the serine-arginine (SR) family of proteins. It functions as a splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. FUSIP1 seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70, and it is required for splicing repression in M-phase cells and after heat shock [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75494].
Product Link
http://www.bethyl.com/product/IHC-00642-T
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