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Rabbit anti-GIT2 Antibody, Affinity Purified

Catalog No.
A302-102A-T
Pack Size
  • 100 µl (1000 µg/ml)
  • 10 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A302-102A-T
Brand
Bethyl Laboratories
Application
IHC
IP
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 500 and 550
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
GIT2
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
ARF GAP GIT2, ARF GTPase-activating protein GIT2, CAT2, CAT-2, cool-associated, tyrosine phosphorylated protein 2, cool-interacting tyrosine-phosphorylated protein 2, G protein-coupled receptor kinase interacting ArfGAP 2, G protein-coupled receptor kinase-interactor 2, GRK-interacting protein 2, Paxillin kinase linker, PKL
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Mouse
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
Not recommended. Use rabbit anti-GIT2 antibody A302-103A.
Immunoprecipitation (IP)
2 - 5 µg/mg lysate
Immunohistochemistry (IHC)
1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Sentence
G-protein-coupled receptor kinase interactor 1 (GIT1) and G-protein-coupled receptor kinase interactor 2 (GIT2) are GTPase-activating proteins for ADP-ribosylation (Arf) GTPases. GIT1 and GIT2 regulate Arf activity and the sequestration of activated G protein-coupled receptors from the surface of the cell. These activities have effects on multiple cellular processes such as cell migration, T-cell activation, and centrosome dynamics. Both GIT proteins also serve as scaffolds to link signaling molecules.
Product Link
http://www.bethyl.com/product/A302-102A
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